Journal: Scientific Reports

Article Title: Complement component 5 promotes lethal thrombosis

doi: 10.1038/srep42714

Figure Lengend Snippet: Mice were injected with histone or saline (45 μg/g, n = 6 per group). Histological findings are show in fig. ( A to D ) at 6 h after histone injection. ( A ) Vehicle group of C5-sufficient, ( B ) Histone group of C5-sufficient, ( C ) Vehicle group of C5-deficient, ( D ) Histone group of C5-deficient. H&E stain. Scale bar, 100 μm. Black allows indicates embolism. The blood samples were collected at 1–6 h after histone injection. Liver function were defined as AST, ALT and LDH levels, and these are shown in ( E – G ), respectively. The figures show the experimental means ± SD. * P < 0.05, ** P < 0.01 vs Histone group of C5-deficient (Scheffe’s test).

Article Snippet: To evaluate liver function, plasma was obtained by centrifugation of the remaining blood at 1500 × g at 4 °C for 10 min. AST, ALT, and LDH levels were also measured by Oriental Yeast Co. Ltd.

Techniques: Injection, Saline, Staining

Journal: Scientific Reports

Article Title: Complement component 5 promotes lethal thrombosis

doi: 10.1038/srep42714

Figure Lengend Snippet: The mice were received a single tail-vein injection of C5a receptor antagonist PMX205 (50 μg/body) or saline. At 10 min after injection of saline or PMX205, the mice in the histone and PMX 205 groups were injected with unfractionated histones. The mice in the control group were injected with saline only. Liver function were defined as AST, ALT and LDH levels, and these are shown in ( A – C ), respectively. The profiles of CD41-CD45 complex (platelet/leukocyte aggregates; PLAs) and CD11b-CD45 positive cells are shown in figure ( D , E ), respectively. The figures show the experimental means ± SD. * P < 0.05 vs PMX205 group (Scheffe’s test).

Article Snippet: To evaluate liver function, plasma was obtained by centrifugation of the remaining blood at 1500 × g at 4 °C for 10 min. AST, ALT, and LDH levels were also measured by Oriental Yeast Co. Ltd.

Techniques: Injection, Saline, Control

Journal: SpringerPlus

Article Title: Highly improved accuracy of the revised PREoperative sarcoma score (rPRESS) in the decision of performing surgery for patients presenting with a uterine mass

doi: 10.1186/s40064-015-1318-7

Figure Lengend Snippet: Positive findings in patients

Article Snippet: In our previous report (Nagai et al. ), univariate analyses revealed that age, serum LDH levels, MRI findings, and endometrial cytology findings were significant factors in the preoperative prediction of uterine sarcoma.

Techniques:

Journal: SpringerPlus

Article Title: Highly improved accuracy of the revised PREoperative sarcoma score (rPRESS) in the decision of performing surgery for patients presenting with a uterine mass

doi: 10.1186/s40064-015-1318-7

Figure Lengend Snippet: Multivariate analysis of statistically significant positive findings

Article Snippet: In our previous report (Nagai et al. ), univariate analyses revealed that age, serum LDH levels, MRI findings, and endometrial cytology findings were significant factors in the preoperative prediction of uterine sarcoma.

Techniques:

Journal: SpringerPlus

Article Title: Highly improved accuracy of the revised PREoperative sarcoma score (rPRESS) in the decision of performing surgery for patients presenting with a uterine mass

doi: 10.1186/s40064-015-1318-7

Figure Lengend Snippet: Parameter estimates of each predictor

Article Snippet: In our previous report (Nagai et al. ), univariate analyses revealed that age, serum LDH levels, MRI findings, and endometrial cytology findings were significant factors in the preoperative prediction of uterine sarcoma.

Techniques:

Journal: SpringerPlus

Article Title: Highly improved accuracy of the revised PREoperative sarcoma score (rPRESS) in the decision of performing surgery for patients presenting with a uterine mass

doi: 10.1186/s40064-015-1318-7

Figure Lengend Snippet: The revised PREoperative sarcoma scoring system (rPRESS)

Article Snippet: In our previous report (Nagai et al. ), univariate analyses revealed that age, serum LDH levels, MRI findings, and endometrial cytology findings were significant factors in the preoperative prediction of uterine sarcoma.

Techniques:

Journal: Open Veterinary Journal

Article Title: Diagnostic utility of measuring lactate dehydrogenase levels and its isoenzyme activities for the evaluation of malignancy in feline pleural effusion and ascitic fluid

doi: 10.5455/OVJ.2022.v12.i5.19

Figure Lengend Snippet: Comparison of LDH levels and LDH isoenzymes activities among the malignant group, the NMNI group, and the infectious group

Article Snippet: LDH levels and LDH isoenzyme subgroup activities were measured in all samples (LSI Medience Co., Tokyo, Japan).

Techniques: Comparison

Journal: Open Veterinary Journal

Article Title: Diagnostic utility of measuring lactate dehydrogenase levels and its isoenzyme activities for the evaluation of malignancy in feline pleural effusion and ascitic fluid

doi: 10.5455/OVJ.2022.v12.i5.19

Figure Lengend Snippet: Comparison of LDH isoenzyme activities in PE and AF among the malignant, NMNI, and infectious groups. Box plots show the median, range, and 25th and 75th quartiles within the groups. LDH level, LDH-3, and LDH-4 activities were significantly higher in the malignant group than those in the NMNI group ( p = 0.007, 0.007, and 0.002, respectively). LDH-1 activity was significantly lower in the malignant group than that in the NMNI group ( p < 0.001). LDH-1 activity was significantly lower in the malignant group than that in the infectious group ( p = 0.031). LDH level and LDH-4 activity were lower in the malignant group than those in the infectious group ( p = 0.015, respectively). Statistical analyses were performed using the Kruskal–Wallis test. Post hoc comparisons were conducted using the Mann–Whitney U test with Bonferroni correction. * p < 0.05, ** p < 0.01; LDH, lactate dehydrogenase; PE, pleural effusion; AF, ascitic fluid; NMNI, non-malignant, non-infectious.

Article Snippet: LDH levels and LDH isoenzyme subgroup activities were measured in all samples (LSI Medience Co., Tokyo, Japan).

Techniques: Comparison, Activity Assay, MANN-WHITNEY

Journal: Toxins

Article Title: In Vivo Evaluation of the Chronic Oral Toxicity of the Marine Toxin Palytoxin

doi: 10.3390/toxins12080489

Figure Lengend Snippet: Scatter plot graphs showing the effects of different doses of PLTX administered daily by gavage on the blood levels of ALT ( A ), AST ( B ), CK ( C ), and LDH ( D ). Data are expressed as means ± SEM from one to seven determinations. * p < 0.05 versus control mice. The respective minimum and maximum reference blood values for each parameter are marked by the pointed lines.

Article Snippet: However, two out of the six mice fed with 0.1 μg/kg PLTX had LDH levels well above the IDEXX reference range for blood LDH, which is between 1105 and 3993 U/L.

Techniques: Control